Stereocontrol within polyketide assembly lines
نویسندگان
چکیده
منابع مشابه
Polyketide stereocontrol: a study in chemical biology
The biosynthesis of reduced polyketides in bacteria by modular polyketide synthases (PKSs) proceeds with exquisite stereocontrol. As the stereochemistry is intimately linked to the strong bioactivity of these molecules, the origins of stereochemical control are of significant interest in attempts to create derivatives of these compounds by genetic engineering. In this review, we discuss the cur...
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ژورنال
عنوان ژورنال: Natural Product Reports
سال: 2016
ISSN: 0265-0568,1460-4752
DOI: 10.1039/c5np00092k